I am getting java.lang.OutOfMemoryError when using Big ANE (In this case Mopub.ane with all the mediation sdks).
i found a solution http://forums.adobe.com/thread/1047755 (setting _JAVA_OPTIONS in .bash_profile) this worked for me in my Macbook. But not working in Windows (setting _JAVA_OPTIONS in Environment Variables) it results in the following behaviour (refer screenshot).
P.S. I tried increasing Xmx values in jvm.ini, No Luck.